Christian M.T. Spahn: search on Z-Library

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1

Structural Snapshots of Actively Translating Human Ribosomes

Behrmann, Elmar, Loerke, Justus, Budkevich, Tatyana V., Yamamoto, Kaori, Schmidt, Andrea, Penczek, Pawel A., Vos, Matthijn R., Bürger, Jörg, Mielke, Thorsten, Scheerer, Patrick, Spahn, Christian M.T.

Journal:

Year:

2015

Language:

english

File:

PDF, 6.24 MB

english, 2015

2

Insights into the assembly and activation of the microtubule nucleator Î³-TuRC

Liu, Peng, Zupa, Erik, Neuner, Annett, BÃ¶hler, Anna, Loerke, Justus, Flemming, Dirk, Ruppert, Thomas, Rudack, Till, Peter, Christoph, Spahn, Christian, Gruss, Oliver J., Pfeffer, Stefan, Schiebel, El

Journal:

Year:

2019

Language:

english

File:

PDF, 14.77 MB

english, 2019

3

Identifying Conformational States of Macromolecules by Eigen-Analysis of Resampled Cryo-EM Images

Pawel A. Penczek, Marek Kimmel, Christian M.T. Spahn

Journal:

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

4

The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre

Fritsch, Johannes, Scheerer, Patrick, Frielingsdorf, Stefan, Kroschinsky, Sebastian, Friedrich, Bärbel, Lenz, Oliver, Spahn, Christian M. T.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

5

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation

Connell, Sean R, Topf, Maya, Qin, Yan, Wilson, Daniel N, Mielke, Thorsten, Fucini, Paola, Nierhaus, Knud H, Spahn, Christian M T

Journal:

Nature Structural and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 786 KB

english, 2008

6

Ribosomal protein L2 is involved in the association of the ribosomal subunits, tRNA binding to A and P sites and peptidyl transfer

Diedrich, Gundo, Spahn, Christian M. T., Stelzl, Ulrich, Schäfer, Markus A., Wooten, Tammy, Bochkariov, Dmitry E., Cooperman, Barry S., Traut, Robert R., Nierhaus, Knud H.

Journal:

The EMBO Journal

Year:

2000

Language:

english

File:

PDF, 320 KB

english, 2000

7

Melatonin protects SHSY5Y neuroblastoma cells from cobalt-induced oxidative stress, neurotoxicity and increased β-amyloid secretion

Gianfranco Olivieri, Christian Hess, Egemen Savaskan, Chuong Ly, Fides Meier, Ginette Baysang, Manfred Brockhaus, Franz Müller-Spahn

Journal:

Journal of Pineal Research

Year:

2001

Language:

english

File:

PDF, 144 KB

english, 2001

8

Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution

Hilal, Tarek, Yamamoto, Hiroshi, Loerke, Justus, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M.T.

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.14 MB

english, 2016

9

Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM

Sengupta, Jayati, Nilsson, Jakob, Gursky, Richard, Spahn, Christian M T, Nissen, Poul, Frank, Joachim

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.08 MB

english, 2004

10

CTER—Rapid estimation of CTF parameters with error assessment

Penczek, Pawel A., Fang, Jia, Li, Xueming, Cheng, Yifan, Loerke, Justus, Spahn, Christian M.T.

Journal:

Ultramicroscopy

Year:

2014

Language:

english

File:

PDF, 4.61 MB

english, 2014

11

The ribosome and the mechanism of protein synthesis

Frank, Joachim, Spahn, Christian M T

Journal:

Reports on Progress in Physics

Year:

2006

Language:

english

File:

PDF, 4.84 MB

english, 2006

12

Knud Hermann Nierhaus 1941–2016

Wilson, Daniel N, Spahn, Christian M T

Journal:

Nature Structural and Molecular Biology

Year:

2016

Language:

english

File:

PDF, 880 KB

english, 2016

13

Heart rate elevations during early sepsis predict death in fluid-resuscitated rats with fecal peritonitis

Rudiger, Alain, Jeger, Victor, Arrigo, Mattia, Schaer, Christian A., Hildenbrand, Florian F., Arras, Margarete, Seifert, Burkhardt, Singer, Mervyn, Schoedon, Gabriele, Spahn, Donat R., Bettex, Dominiq

Journal:

Intensive Care Medicine Experimental

Year:

2018

Language:

english

File:

PDF, 902 KB

english, 2018

14

Translatomics: The Global View of Translation

Zhao, Jing, Qin, Bo, Nikolay, Rainer, Spahn, Christian M. T., Zhang, Gong

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 2.20 MB

2019

15

Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions

Christian M.T. Spahn, Roland Beckmann, Narayanan Eswar, Pawel A. Penczek, Andrej Sali, Günter Blobel, Joachim Frank

Journal:

Year:

2001

Language:

english

File:

PDF, 785 KB

english, 2001

16

Solution Structure of the E. coli 70S Ribosome at 11.5 Å Resolution

Irene S Gabashvili, Rajendra K Agrawal, Christian M.T Spahn, Robert A Grassucci, Dmitri I Svergun, Joachim Frank, Pawel Penczek

Journal:

Year:

2000

Language:

english

File:

PDF, 640 KB

english, 2000

17

EF-G and EF4: translocation and back-translocation on the bacterial ribosome

Yamamoto, Hiroshi, Qin, Yan, Achenbach, John, Li, Chengmin, Kijek, Jaroslaw, Spahn, Christian M. T., Nierhaus, Knud H.

Journal:

Nature Reviews Microbiology

Year:

2013

Language:

english

File:

PDF, 2.89 MB

english, 2013

18

Structural Insights into Membrane Interaction and Caveolar Targeting of Dynamin-like EHD2

Shah, Claudio, Hegde, Balachandra G., Morén, Björn, Behrmann, Elmar, Mielke, Thorsten, Moenke, Gregor, Spahn, Christian M.T., Lundmark, Richard, Daumke, Oliver, Langen, Ralf

Journal:

Year:

2014

Language:

english

File:

PDF, 3.20 MB

english, 2014

19

Visualization of tRNA Movements on the Escherichia coli 70S Ribosome during the Elongation Cycle

Rajendra K. Agrawal, Christian M. T. Spahn, Pawel Penczek, Robert A. Grassucci, Knud H. Nierhaus and Joachim Frank

Journal:

The Journal of Cell Biology

Year:

2000

Language:

english

File:

PDF, 4.62 MB

english, 2000

20

Haptoglobin Preserves Vascular Nitric Oxide Signaling During Hemolysis

Schaer, Christian A, Deuel, Jeremy W, Schildknecht, Daniela, Mahmoudi, Leila, Garcia-Rubio, Ines, Owczarek, Catherine, Schauer, Stefan, Kissner, Reinhard, Banerjee, Uddyalok, Palmer, Andre F, Spahn, D

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2015

Language:

english

File:

PDF, 5.27 MB

english, 2015

21

Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor

Krupp, Ferdinand, Said, Nelly, Huang, Yong-Heng, Loll, Bernhard, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M.T., Wahl, Markus C.

Journal:

Year:

2019

Language:

english

File:

PDF, 8.74 MB

english, 2019

22

Von der „Mikrosomenfraktion“ zur atomaren Ribosomenstruktur

Bommer, Ulrich-Axel, Spahn, Christian M. T.

Journal:

Year:

2019

File:

PDF, 455 KB

2019

23

Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation

Spahn, Christian MT, Gomez-Lorenzo, Maria G, Grassucci, Robert A, Jørgensen, Rene, Andersen, Gregers R, Beckmann, Roland, Penczek, Pawel A, Ballesta, Juan PG, Frank, Joachim

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 577 KB

english, 2004

24

Estimation of variance in single-particle reconstruction using the bootstrap technique

Pawel A. Penczek, Chao Yang, Joachim Frank, Christian M.T. Spahn

Journal:

Journal of Structural Biology

Year:

2006

Language:

english

File:

PDF, 431 KB

english, 2006

25

P2-140: Mitochondrial failure in a transgenic mice model of Alzheimer's disease with plaques and tangles

Rhein, Virginie, Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Hurs, Dröse, Stefan, Brandt, Ulrich, Müller-Spahn, Franz, Czech, Christian, Goetz, Jurgen, Eckert, Anne

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

26

Determination of triamterene and its main metabolite hydroxytriamterene sulfate in human urine by capillary electrophoresis using ultraviolet absorbance and laser-induced fluorescence detection

Christian Horstkötter, Susan Kober, Hildegard Spahn-Langguth, Ernst Mutschler, Gottfried Blaschke

Journal:

Journal of Chromatography B

Year:

2002

Language:

english

File:

PDF, 350 KB

english, 2002

27

Localization and dynamic behavior of ribosomal protein L30e

Halic, Mario, Becker, Thomas, Frank, Joachim, Spahn, Christian M T, Beckmann, Roland

Journal:

Nature Structural and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 365 KB

english, 2005

28

Architecture of the Protein-Conducting Channel Associated with the Translating 80S Ribosome

Roland Beckmann, Christian M.T. Spahn, Narayanan Eswar, Jürgen Helmers, Pawel A. Penczek, Andrej Sali, Joachim Frank, Günter Blobel

Journal:

Year:

2001

Language:

english

File:

PDF, 449 KB

english, 2001

29

Opioid withdrawal increases transient receptor potential vanilloid 1 activity in a protein kinase A-dependent manner

Spahn, Viola, Fischer, Oliver, Endres-Becker, Jeannette, Schäfer, Michael, Stein, Christoph, Zöllner, Christian

Journal:

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

30

Strategies to reduce the use of blood products

Theusinger, Oliver M., Felix, Christian, Spahn, Donat R.

Journal:

Current Opinion in Anaesthesiology

Year:

2012

Language:

english

File:

PDF, 254 KB

english, 2012

31

Editorial

Wilson, Daniel, Spahn, Christian, Yusupov, Marat

Journal:

Journal of Molecular Biology

Year:

2016

Language:

english

File:

PDF, 83 KB

english, 2016

32

Structure and Dynamics of the Mammalian Ribosomal Pretranslocation Complex

Tatyana Budkevich, Jan Giesebrecht, Roger B. Altman, James B. Munro, Thorsten Mielke, Knud H. Nierhaus, Scott C. Blanchard, Christian M.T. Spahn

Journal:

Year:

2011

Language:

english

File:

PDF, 2.15 MB

english, 2011

33

Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice

Katrin Schuessel, Stephanie Schäfer, Thomas A. Bayer, Christian Czech, Laurent Pradier, Franz Müller-Spahn, Walter E. Müller, Anne Eckert

Journal:

Neurobiology of Disease

Year:

2005

Language:

english

File:

PDF, 453 KB

english, 2005

34

Revealing the Energy Landscapes of Ribosome Function

Whitford, Paul C., Spahn, Christian M.T., Blanchard, Scott C., Onuchic, Jose' N., Sanbonmatsu, Karissa Y.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 37 KB

english, 2011

35

Excited states of ribosome translocation revealed through integrative molecular modeling

Paul C. Whitford, Aqeel Ahmed, Yanan Yu, Scott P. Hennelly, Florence Tama, Christian M. T. Spahn, José N. Onuchic and Karissa Y. Sanbonmatsu

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.87 MB

english, 2011

36

Multifaceted Stoichiometry Control of Bacterial Operons Revealed by Deep Proteome Quantification

Zhao, Jing, Zhang, Hong, Qin, Bo, Nikolay, Rainer, He, Qing-Yu, Spahn, Christian M. T., Zhang, Gong

Journal:

Frontiers in Genetics

Year:

2019

Language:

english

File:

PDF, 5.89 MB

english, 2019

37

Direct three-dimensional localization and positive identification of RNA helices within the ribosome by means of genetic tagging and cyro-electron microscopy

Christian MT Spahn, Robert A Grassucci, Pawel Penczek, Joachim Frank

Journal:

Year:

1999

Language:

english

File:

PDF, 168 KB

english, 1999

38

Absence of CCR6 Inhibits CD4+ Regulatory T-Cell Development and M-Cell Formation inside Peyer's Patches

Andreas Lügering, Martin Floer, Sabine Westphal, Christian Maaser, Thomas W. Spahn, M. Alexander Schmidt, Wolfram Domschke, Ifor R. Williams, Torsten Kucharzik

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 887 KB

english, 2005

39

Localization of the Ribosomal Protection Protein Tet(O) on the Ribosome and the Mechanism of Tetracycline Resistance

Christian M.T. Spahn, Gregor Blaha, Rajendra K. Agrawal, Pawel Penczek, Robert A. Grassucci, Catharine A. Trieber, Sean R. Connell, Diane E. Taylor, Knud H. Nierhaus, Joachim Frank

Journal:

Year:

2001

Language:

english

File:

PDF, 525 KB

english, 2001

40

The lymphotoxin-β receptor is critical for control of murine Citrobacter rodentium–induced colitis

Thomas W. Spahn, Christian Maaser, Lars Eckmann, Jan Heidemann, Andreas Lügering, Rodney Newberry, Wolfram Domschke, Hermann Herbst, Torsten Kucharzik

Journal:

Gastroenterology

Year:

2004

Language:

english

File:

PDF, 526 KB

english, 2004

41

Human intestinal microvascular endothelial cells (HIMEC) express toll-like receptor 5—a potential binding partner for bacterial Flagella

Maaser, Christian, Heidemann, Jan, Kucharzik, Torsten, Spahn, Thomas W., Von Eiff, Christoph, Binion, David G., Domschke, Wolfram, Luegering, Norbert

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 266 KB

english, 2003

42

Patient Blood Management Bundles to Facilitate Implementation

Meybohm, Patrick, Richards, Toby, Isbister, James, Hofmann, Axel, Shander, Aryeh, Goodnough, Lawrence Tim, Muñoz, Manuel, Gombotz, Hans, Weber, Christian Friedrich, Choorapoikayil, Suma, Spahn, Donat

Journal:

Transfusion Medicine Reviews

Year:

2016

Language:

english

File:

PDF, 367 KB

english, 2016

43

Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution

Nikolay, Rainer, Hilal, Tarek, Qin, Bo, Mielke, Thorsten, Bürger, Jörg, Loerke, Justus, Textoris-Taube, Kathrin, Nierhaus, Knud H., Spahn, Christian M.T.

Journal:

Year:

2018

Language:

english

File:

PDF, 8.21 MB

english, 2018

44

A dose-rate effect in single-particle electron microscopy

James Z. Chen, Carsten Sachse, Chen Xu, Thorsten Mielke, Christian M.T. Spahn, Nikolaus Grigorieff

Journal:

Journal of Structural Biology

Year:

2008

Language:

english

File:

PDF, 1.38 MB

english, 2008

45

S12.41 Altered mitochondrial respiration and energy metabolism in brain cells from transgenic Alzheimer’s disease mice

Virginie Rhein, Ginette Baysang, Fides Meier, Laurence Ozmen, Horst Bluethmann, Stefan Dröse, Ulrich Brandt, Franz Müller-Spahn, Christian Czech, Jurgen Götz, Anne Eckert

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2008

Language:

english

File:

PDF, 86 KB

english, 2008

46

The elongating ribosome: structural and functional aspects

Nierhaus, Knud H., Beyer, Dieter, Dabrowski, Marylena, Schäfer, Markus A., Spahn, Christian M. T., Wadzack, Jörg, Bittner, Jörg-Uwe, Burkhardt, Nils, Diedrich, Gundo, Jünemann, Ralf, Kamp, Detlev, Vos

Journal:

Biochemistry and Cell Biology

Year:

1995

Language:

english

File:

PDF, 1.50 MB

english, 1995

47

Treatment of behavioural, cognitive and circadian rest-activity cycle disturbances in Alzheimer's disease: haloperidol vs. quetiapine

Savaskan, Egemen, Schnitzler, Corina, Schröder, Carmen, Cajochen, Christian, Müller-Spahn, Franz, Wirz-Justice, Anna

Journal:

The International Journal of Neuropsychopharmacology

Year:

2006

Language:

english

File:

PDF, 103 KB

english, 2006

48

Cryo-EM structure of the Shigella type III needle complex

Lunelli, Michele, Kamprad, Antje, BÃ¼rger, JÃ¶rg, Mielke, Thorsten, Spahn, Christian M. T., Kolbe, Michael, Kubori, Tomoko

Journal:

Year:

2020

File:

PDF, 17.73 MB

2020

49

Induction of Colitis in Mice Deficient of Peyer's Patches and Mesenteric Lymph Nodes Is Associated with Increased Disease Severity and Formation of Colonic Lymphoid Patches

Thomas W. Spahn, Hermann Herbst, Paul D. Rennert, Norbert Lügering, Christian Maaser, Mathias Kraft, Adriano Fontana, Howard L. Weiner, Wolfram Domschke, Torsten Kucharzik

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 3.34 MB

english, 2002

50

Similarities and differences in the inhibition patterns of thiostrepton and viomycin: Evidence for two functionally different populations of P sites when occupied with AcPhe-tRNA

Ulrike R. Kutay, Christian M.T. Spahn, Knud H. Nierhaus

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1990

Language:

english

File:

PDF, 352 KB

english, 1990

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